Defragment files that get missed by most programs

Some files never seem to get defragmented by software because the system files are in use. Files like the swap file. You could use a windows pe or bartpe boot disk to defrag these files or use pagedefrag and have them defragmented at boot time. There are other work arounds but pagedefrag seems the quickest and easy to do.

http://support.microsoft.com/kb/227350

http://en.wikipedia.org/wiki/PageDefrag

http://technet.microsoft.com/sysinternals/bb897426.aspx